(Graphic) Abnormal baby born in Karachi pakistan

Oh wow! That's a pretty crazy looking baby! In no way am I making fun of this because it must be a horrible thing to live with, but I think that looks badass!

A good point....

What genes are related to harlequin ichthyosis?
Mutations in the ABCA12 gene cause harlequin ichthyosis. The ABCA12 gene provides instructions for making a protein that is essential for the normal development of skin cells. This protein plays a major role in the transport of fats (lipids) in the outermost layer of skin (the epidermis). Some mutations in the ABCA12 gene prevent the cell from making any ABCA12 protein. Other mutations lead to the production of an abnormally small version of the protein that cannot transport lipids properly. A loss of functional ABCA12 protein disrupts the normal development of the epidermis, resulting in the hard, thick scales characteristic of harlequin ichthyosis.

Read more about the ABCA12 gene.

How do people inherit harlequin ichthyosis?
This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

With my curiosity now fueled, the question is...... is the condition any less rare in Pakistan?

Lol @ some of you conspiracy theorist loons.

This is a Harlequin baby.... A very sad skin disorder that has a rarity of something like 1 in 6 million. These babies can live and many do live well into adulthood. They have to liberally apply an Acutane-like substance, believe it or not, to prevent their skin from drying out.

I suggest some of you, like Aaron_Ward, do some research before you open your mouth. It's a very interesting topic although not something I would ever wish on anyone's child.

Depleted Uranium munitions - the gift that keeps on giving. We will all see more and more of this happening wherever we have fought using DU.

there's been plenty of babies born with this condition, and worse. It seems to be the places where the corporations have raped the land and the people and now the pregnant mothers are full of all chemicals that are slowly killing them whilst deforming their babies.

well you can make horrible comments if you want, but I think its really sad- don't forget thats an actual living person!

It's called a Harlequin baby - it is a severe skin condition

WHAT HAS BEEN SEEN CANNOT BE UNSEEN!

usa we did more damage over thiier than the terrorists did to the towers just pick up and leave you think your christ smiles on you for this or does your devil smile on you
if they exist i dont they appreciate what has happened

wow thats a scary lookin baby

That has to be fake man.... it has to....

I think it has that Sarah Palin gene.