Human genome reveals signs of recent evolution

// added June 23, 2008 // 59 comments //
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celestialceiling
New genetic evidence suggests that evolution has continued to shape our species powerfully over the past 100,000 years. By looking for signals based on how much DNA mutates over generations, researchers found clues that as much as 10 percent of the human genome may be linked to these recent adaptive genetic changes.

Cornell University population geneticist Scott Williamson and colleagues analyzed over a million genetic variations in DNA samples from 24 individuals, including African Americans, European Americans, and Chinese. They were looking for regions in the genome where a beneficial mutation is carried by everyone in a population. Then, by looking at the variability in the DNA surrounding the mutation, the team could figure out how long ago the mutation spread through the population.

More than a hundred sites in the genome showed strong evidence of recent selection, including genes that affect muscle tissue, hair, hearing, immune-system function, skin pigmentation, sense of smell, and the body’s response to heat stress.


by Jennifer Barone
Discover Magazine
http://discovermagazine.com/2008/jan/human-genome-reveals-signs-of-recent-evolut...
Localizing Recent Adaptive Evolution in the Human Genome
http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030090
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59 comments // Human genome reveals signs of recent evolution

  • CicatrizJCP
    • 0
      CicatrizJCP  
    • Maybe the genome of our population will mutate within the next 50 years to make us impervious to the effects of global warming, famine from rising food costs, nuclear war, and inept authorities...

      Then we wouldn't have to worry about these things anymore. Come on nature, throw us a bone.

    • 1 year ago
  • shadowtrekker
    • 0
      shadowtrekker  
    • there is a big difference between evolution and adaptation, It's funny that the folks who don't know this are talking about how happy they are to be evolving - into what? something dumber?

    • 1 year ago
  • RoxyB
  • muffin2062
    • 0
      muffin2062  
    • while evolution and adaption are linked they do not neccessarily prove each other. You can not say that since there is adaptation then there must have been evolution.

    • 1 year ago
  • jjmaster
    • 0
      jjmaster  
    • CO2, lead, mercury, radiation, strontium 90, pesticides, pharmecuetical drugs, acid rain, gmbh, red die no#5, etc., etc., of course we will see genetic changes/mutations... Have any of you studied the evolution of the scavenger cockroach? They are very adaptable!

    • 1 year ago
  • celestialceiling
  • thisismattholt
  • dkl165
  • flyingkick
  • benjaminV
    • 0
      benjaminV  
    • Hey Creationists! Oh, wait, 'Intelligent Design' believers:

      Your beliefs are not valid. Wake up, shake off that constricting crap called fundamentalism, and get with the picture!

    • 1 year ago
  • thisismattholt
    • 0
      thisismattholt  
    • benjaminV:

      Benji boy,

      and I do stress boy, because you lack the knowledge to back up your belief with anything. Ironically,that sounds like "faith" a bit.

      You seem to be constricted by the one sided way your 4th grade textbook only presents things.

    • 1 year ago
  • Vierotchka
  • mo1y
    • 0
      mo1y  
    • Amazing, their still trying to find the missing link. When I was young, the search for the missing link between Ape and man was being looked for to prove evolution.
      The missing link was never found. Now they are looking in DNA. Of course, who can argue with DNA. DNA is like statistic. You can make statistic say anything you want. The same with DNA.
      Knowledge of DNA has been around for about 50 years. It is very large, and very complicated. But geniuses who can support evolution with DNA will get grant money forever.
      Personnally, I do not care, but I sort of like Intelligent Selection, or whatever. Or maybe we are some high school project for a child in a distant universe, and then there's God.
      God had it right in Genisis, when he said "then there was light. While the "Big Bang" theory, states the universe started with a Bang.
      But wait a minute, in order to have a Bang you have to have air. There is no air in outer space, therefore no bang.
      If there was no bang, then God was right, because there would have been a burst of light without a bang at the begining of the universe.
      God 1 Pop Science 0.

      Maybe God was right, and evolution is wrong. Hmmn. Now the evolutional zealots are going to label me to death. Evolutional zealots do not argue with facts, they just label you.
      I hope you got a chuckle out of this diatribe of mine.

    • 1 year ago
  • flyingkick
    • 0
      flyingkick  
    • mo1y:

      OK, even if evolution and the big bang were proven wrong, that wouldn't in any logical way prove that God exists. That's a huge jump that doesn't make any sense.

      You're post is funny because you accuse evolution zealots of being labelers when you yourself just labeled all of them, lol.

      Don't confuse science with religion. You should be able to maintain your own spirituality while thinking critically about the universe.

    • 1 year ago
  • thisismattholt
    • 0
      thisismattholt  
    • Scientists have repeated this throughout history, classifying mutations as evidence to evolution.

      Why wouldn't they want to be the first to find a provable link to evolution? After all, there are numerous cash awards among other things for it...

      But they know as well as anyone, we're looking at mutations, not evolutions.

      We should not consider a beneficial mutation a process of evolution.

      We all already know this though: an ambiguous change may often times have an unexpected positive secondary effect, not due to anything but chance.

    • 1 year ago
  • Clambert
    • 0
      Clambert  
    • Everything is evolving right now anyway so it only makes sense, with all the crazy changes our environment is taking on that only means were going to have to adapt. Too bad the whole process takes so long, it would be crazy to see all the new things popping up.

    • 1 year ago
  • My_Preserver
  • timbolinder
  • Neghie
    • 0
      Neghie  
    • Yeah evolutions happenin'! I'm startin' to see a whole bunch o' white girls with black girl video bootys. What's going on?!

    • 1 year ago
  • Joe_Leo
    • 0
      Joe_Leo  
    • I cant read much about 'mutation' or 'evolution' before my mind wanders in the general direction of x-men :/

      one day maybe

    • 1 year ago
  • jinofcoolnes
    • 0
      jinofcoolnes  
    • I would say if you still dont think evolution is real by now,i think you need to have a Real Big talk with yourslef.

      This new just adds more proof to the proven.

    • 1 year ago
  • thisismattholt
  • 24French
  • torybart
  • BretByron
  • jinofcoolnes
  • wannabedoc
  • LarzNero
  • BretByron
  • Vierotchka
  • mooseydoom
    • 0
      mooseydoom  
    • Another showing of evolution is all the different kinds of people there are. I'm not just talking about the difference between black and white either. If you look at caucasions we have a large varieties of different people who have adapted from different parts of the world. For example, you have the irish with different body traits than say, Germans.

    • 1 year ago
  • ReddFeary83
    • 0
      ReddFeary83  
    • When did the idea come into play that evolution ever stopped? Look at photos and memorabilia from back in the day: everybody is different in each generation. Sure, the style's different, but that's not the only thing. Shapes of faces, body type, posture, etc. These are all noticeably different as time passes. As many I'm sure like to attribute this to changing times, they are so wrong. Evolution is a small step kinda process; we're even taller today than many of those that came before us. How is this not seen as evolution? Just a curious thing to see that it's assumed something that's totally biological and in our genetics just decided one day to nap. Yeah, right.......

    • 1 year ago
  • wannabedoc
    • 0
      wannabedoc  
    • ReddFeary83:

      Increase in height is less due to genes and more due to reaching genetic potential as a result of better diets and lifestyles now.
      The Aztecs would have had about the same genetic height potential as we do, but we have better diets.

    • 1 year ago
  • ReddFeary83
    • 0
      ReddFeary83  
    • ReddFeary83:

      True, but Aztecs also believed in a blood god, sacrificing human beings to win the god's favor. It could be considered that it's due to better dieting; but then that also makes me wonder about America's obesity rate. They may have had the potential, but they lacked the fundamentals to understand this.

    • 1 year ago
  • MajorMajorMajorMajor
    • 0
      MajorMajorMajorMajor  
    • ReddFeary83:

      "True, but Aztecs also believed in a blood god, sacrificing human beings to win the god's favor."

      Their beliefs have nothing to do with anything. A diet of mainly of corn just doesn't provide the nutrition needed for taller people.

    • 1 year ago
  • ReddFeary83
    • 0
      ReddFeary83  
    • ReddFeary83:

      No, it sure doesn't; but that was what they had. Just having the potential doesn't always make a fact. Everybody has a potential for something, but it doesn't mean that the potential in question could actually be achieved. With or without certain factors, that's all it is: potential. The capability does not prove the functionality. They may have been capable, and had the potential, but there's no way to go back and prove or disprove that they could achieve a taller height.

    • 1 year ago
  • wannabedoc
    • 0
      wannabedoc  
    • ReddFeary83:

      You're misunderstanding: the genetic potential for height hasn't increased much over the last few thousand years. Therefore genes are nothing to do with increased height it is diet.
      What does blood god sacrificing have to do with anything at all?!

    • 1 year ago
  • ReddFeary83
    • 0
      ReddFeary83  
    • ReddFeary83:

      Wow, came in late on that one did ya? It was merely an indication of where they were in their common knowledge. It wasn't typed to add a platform for everyone to stand on and argue about. How about I edit that out, and you can respond to what else I typed? There are better diets and lifestyles, but do you honestly believe they are being followed by every human being on the planet? I highly doubt it, and that's putting it lightly. Utilizing diet will only go so far, after that it becomes a matter of nature. The possibility does not prove the capability or functionality. All this mess from a simply stated thing. Height was SIMPLY an EXAMPLE, did you even read the entirety of my first statement? I'm guessing no. But, hey, you can make informed arguments, so why bother you to read the ENTIRE statement BEFORE the stupid Aztec thing? Too much to expect I suppose. Oh well.......

    • 1 year ago
  • BenDorries
    • 0
      BenDorries  
    • This is SO AWESOME to me. I'm kind of an anthropology nerd sometimes and this kind of stuff is my bread and butter.

      I'd love to see exactly what genes have changed and how.

    • 1 year ago
  • eldamon
  • eggsdenison
  • Argon18
    • 0
      Argon18  
    • eggsdenison:

      What I could never figure out was why couldn't God use evolution? You would think that an omnipotent and omniscient being would use the best methods to serve the purpose

    • 1 year ago
  • eggsdenison
    • 0
      eggsdenison  
    • eggsdenison:

      Right????? Why would God create a species(man) that seems to accomodate the lowest common denomination of being? Iguess that's where the saying "you are only as strong as your weakest link" comes from.

    • 1 year ago
  • Argon18
    • 0
      Argon18  
    • eggsdenison:

      I don't get that part, why would God create something so static that it couldn't grow and improve? Isn't it arrogant to think that even if it started out at a lower stage that it never could get to the highest?

    • 1 year ago
  • eggsdenison
    • 0
      eggsdenison  
    • eggsdenison:

      Hard to say maybe he did... but all these a**holes who think that they are channels of the lord's word would never tell us the truth because it would eat away at the power they have gained in their lives by pretending to be preachers. And whenever you push for answers you get the old "you just got to have faith" line.

    • 1 year ago
  • wannabedoc
    • 0
      wannabedoc  
    • eggsdenison:

      I agree, it is totally arrogant and small-minded to believe that God is great, but not great enough to create such a brilliant process that enables us to adapt to our environment to survive climatic changes. In fact, it's ridiculous to think that God is that simple.

    • 1 year ago
  • MajorMajorMajorMajor
  • Argon18
    • 0
      Argon18  
    • Living past 100 has a lot more to do with adapting the genome and using methods to enhance the body than with the evolution of it.

      No one is immune to it but like when taking species of animals that have certain characteristics and breeding them together to enhance those charateristics or produce new ones makes evolution apply less.

    • 1 year ago
  • mooseydoom
    • 0
      mooseydoom  
    • ahh, the beauty of confirming what we already know.

      Evolution is a real thing, the idea that humans are immune to it is just silly. Who knows how we will change in the future.

      One theory of mine is that we will soon be living well past 100. With how more and more of the population are having kids late in life, this is a real possibility.

    • 1 year ago
  • wannabedoc
    • 0
      wannabedoc  
    • mooseydoom:

      No, unfortunately it is more probable that we will live less.
      The huge increase in life expectancy has been due to better diets, exercise, lifestyle etc.
      Unfortunately there has been many studies indicating links between benefits of fertility and disadvantages to longevity.
      I.e. Children are born with fewer complications and less risk to the mother at a cost of shorter life.
      (Note how trees live for thousands of years as they do not give birth or have 'true' sexual reproduction)
      More babies = more of these genes passed on = more people who have better mothering/fathering potential but shorter lifespans.
      The evility of the X-Y antagonism :(

    • 1 year ago
  • Neghie
    • 0
      Neghie  
    • mooseydoom:

      wannabe,
      Couldn't that be rectified by selective breeding? I mean, it's a slippery slope, but, if you were to take two people whose genetic background is free from degenerative diseases, I mean I know you can't be completely free, but if certain people are precluded to procreate, and certain people with better genes and health keep spittin' out babies, then people could live longer, maybe on account of good genes?

    • 1 year ago
  • mooseydoom
    • 0
      mooseydoom  
    • mooseydoom:

      both of you provide a very good point, I tend to agree more with Neghie though.

      For more information there was a study by Michael R. Rose on fruit flies. Where they prevented them from breeding until much latter stages in life. They're findings where that they could increase the average life span about 3 times what it was before the study.

    • 1 year ago
  • wannabedoc
    • 0
      wannabedoc  
    • mooseydoom:

      No, because how would you know how long they are going to live before they've had children?
      Unless you're suggesting eugenics?
      Anyway, this will not happen. Due to climate change and exponential population growth, it is increasingly liekly that life expectancy will shoot down for a few hundred years while survival of the fittest competes over food (live fast die young increase progeny).
      Woe is genome.

    • 1 year ago
  • Argon18
    • 0
      Argon18  
    • So I guess that shows evidence that genes are still adapting the the enviroment.

      That evidence sort of add less weight to the theory that when people use tools the change the enviroment to suit the people that evolution stops.

      Maybe it's just slowed down a lot.

    • 1 year ago
  • torybart
    • 0
      torybart  
    • Argon18:

      i don't think that evolution has stopped or even slowed, in humans evolution is just effecting things other than physical characteristics. the human brain will continue to evolve at a very fast rate. but im no scientists this just seems to make sense because of the amount of dependence our species now has on brain function

    • 1 year ago
  • celestialceiling
    • 0
      celestialceiling  
    • My teeth have been aching lately, and I find myself chewing on pens - like a child during "teething."

      Then I looked closely at my teeth and I noticed that my upper Pre-Molars seem to be DIVIDING like CELLS.

      Each Molar looks like a SET of two teeth, and the gap is widening.

      Link this information with the fact that dentists have actually filled in several of my rear molars with fillings. Proof that the dentists noticed these widening gaps years ago.

      Could this be some form of evolution?

      Many of my friends say they have jaw pains.
      Anyone else notice this or other weird signs of change?

    • 1 year ago
  • pirho338
    • 0
      pirho338  
    • celestialceiling:

      that sounds like your wisdom teeth? most people experience pain due to their wisdom teeth, which often start coming in and stopping at random times throughout early adulthood. Maybe people will evolve to the point that their teeth come in earlier and earlier until the wisdom teeth come in with the rest of their teeth in early adolescence?

    • 1 year ago
  • wannabedoc
  • evanessan
    • 0
      evanessan  
    • celestialceiling:

      Oh yeah you are not alone in this observation. My wisdom were taken out: no more weird pains from having too many teeth in my modern homo Sapien mouth, right? A couple of years later and the pain/ head aches are back, my teeth are doing the same thing that you described and now my jaw does this painful popping sensation if I don't do some cardiovascular exercise for that day. We need an actual Anthropologist to tell us what is going on.

    • 1 year ago

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