Nanotechnology based stem cell therapies repair damaged heart muscles
" Regenerative medicine is an area in which stem cells hold great promise for overcoming the challenge of limited cell sources for tissue repair. Stem cell research is being pursued vigorously in laboratories all over the world (except in the U.S., where federal funding for embryonic stem cell research has been severely restricted by the current administration) in the hope of achieving major medical breakthroughs. Scientists are striving to create therapies that rebuild or replace damaged cells with tissues grown from stem cells and offer hope to people suffering from cancer, diabetes, cardiovascular disease, spinal-cord injuries, and many other disorders.
Embryonic stem cells are pluripotent. That means that during normal embryogenesis – the process by which the embryo is formed and develops – human embryonic stem cells can differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. Researchers have also found undifferentiated cells – adult stem cells – in children and adults. Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not controversial because the production of adult stem cells does not require the creation or destruction of an embryo.
Often, adult stem cells are not pluripotent but multipotent. That means they can differentiate only into a limited variety of cell type. One such example are mesenchymal stem cells (MSC) – adult stems cells found in bone marrow which can be differentiated into bone, cartilage, fat, and connective tissues – which offer tremendous potential for the repair and or regeneration of damaged tissues and organs..."
Embryonic stem cells are pluripotent. That means that during normal embryogenesis – the process by which the embryo is formed and develops – human embryonic stem cells can differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. Researchers have also found undifferentiated cells – adult stem cells – in children and adults. Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not controversial because the production of adult stem cells does not require the creation or destruction of an embryo.
Often, adult stem cells are not pluripotent but multipotent. That means they can differentiate only into a limited variety of cell type. One such example are mesenchymal stem cells (MSC) – adult stems cells found in bone marrow which can be differentiated into bone, cartilage, fat, and connective tissues – which offer tremendous potential for the repair and or regeneration of damaged tissues and organs..."
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