tagged w/ Investigational New Drug
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A family of 6 in California became the first recipients in the United States of an intravenous milk thistle (Silybum marianum, Asteraceae) fruit (seed) extract to treat mushroom poisoning in January of 2007. The US Food and Drug Administration permitted emergency use of the drug Legalon Sil® (Madaus Pharma, Brussels; div. of Madaus AG, Cologne, Germany) for the patients, and 5 of the victims survived the poisoning.
Legalon extract, the world’s first pharmaceutical-grade milk thistle extract, is made from the fruits (often called seeds) of milk thistle, standardized to 80% flavonolignans (silibinin [silybin], silydianin, and silychristin). Numerous published animal studies and human clinical trials have shown that milk thistle extract is safe, has antioxidant properties, assists in regeneration of RNA (ribonucleic acid) in the liver to create new hepatocytes, and eliminates toxins from the liver. The leaves of milk thistle, native to the Mediterranean area, have been used both as an edible plant and as a liver remedy in traditional medicine since Greco-Roman times.
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The stuff from the local health food store would be great too. Milk thistle has been used for over 3,000 years.A family of 6 in California became the first recipients in the United States of an... more
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