tagged w/ brain injury
The damaging effect of a traumatic brain injury, due to a car crash or hard blow to the head continues to progress and evolve for many months, a new Australian research has found.
The study, conducted at the Melbourne University, underscores the fragility of the brain but it has also uncovered a broad"window"in which effective treatment could improve a patient's outcome, according to a report in 'The Australian' newspaper. http://www.indiareport.com/India-usa-uk-news/latest-news/928634/Health/10/11/10The damaging effect of a traumatic brain injury, due to a car crash or hard blow to... more
A short documentary I've put together about the artist Simon Haw. I felt a really strong connection with Simon when I met him and although I didn't fully understand everything he was telling me on the day of filming, after going through the footage, I began to interpret and infer things about his backstory and inner emotional life. I hope you find something interesting in here too.
Filmed at Henshaws Arts and Crafts Centre, Knaresborough, Yorkshire, UK.
Check out henshaws.org.uk if you like what you see.A short documentary I've put together about the artist Simon Haw. I felt a really... more
A mother accused of murdering her disabled son has described in court how she told him that she loved him before administering a heroin overdose.
Frances Inglis, 57, of Dagenham, Essex, denies murdering Thomas Inglis, 22, on 21 November 2008 and an earlier attempt to kill him on 4 September 2007.
Mr Inglis was fatally injected with heroin at his Hertfordshire care home.
The Old Bailey jury heard she injected his arm and thighs after saying: "Everything's going to be fine."A mother accused of murdering her disabled son has described in court how she told him... more
Crazy as it sounds, alcohol may one day be given to people with brain injuries to help them recover.
The idea has arisen from a study of 38,000 people with head injuries, which found that those with alcohol in their blood were more likely to survive. For every 100 people who died when stone-cold sober, only 88 died with ethanol – the kind of alcohol in drinks – in their veins.Crazy as it sounds, alcohol may one day be given to people with brain injuries to help... more
Brain injuries are a hell like no other. In the “old days”--someone with a head injury would be described as “just not being right in the head” after that. Now we medicate people to control the symptoms rather than figuring out how to fix what went wrong. Medicating people for things that can be fixed with our own human abilities is a scary kind of Science.
Thank goodness it’s not the only kind of Science.
Here's a story from an ARTIST--now author--who really knows what it's like--and shares. She BEAT brain injuries that left her blind for FIVE years--now she can SEE, and is WELL and worried as heck about the lack of meaningful treatment of our vet's with TBI's and the rash of suicides among our soldiers and veterans. We need to talk about fixing the brain!Brain injuries are a hell like no other. In the “old days”--someone with a... more
The current standard practice of giving infants and children 100 percent oxygen to prevent brain damage caused by oxygen deprivation may actually inflict additional harm, researchers at UT Southwestern Medical Center have found.
Brain damage caused by oxygen deprivation, known as hypoxic-ischemic brain injury, is one of the most common causes of death and long-term neurological damage among infants and children. This can happen during birth trauma, near drowning and other crises.
The UT Southwestern researchers found that mice treated with less than a minute of 100 percent oxygen after a hypoxic-ischemic brain injury suffered far greater rates of brain-cell death and coordination problems similar to cerebral palsy than those allowed to recover with room air.
"This study suggests 100 percent oxygen resuscitation may further damage an already compromised brain," said Dr. Steven Kernie, associate professor of pediatrics and developmental biology and senior author of the study, which appears in the July issue of the Journal of Cerebral Blood Flow & Metabolism.
Most of the damage involved cells that create myelin, a fatty substance that insulates nerve cells and allows them to transmit electrical signals quickly and efficiently. Infants have much less myelin than adults; as myelin develops in children they become more coordinated. Areas of the brain with dense areas of myelin appear white, hence the term "white matter."
"Patients with white-matter injuries develop defects that often result in cerebral palsy and motor deficits," Dr. Kernie said.
Myelin comes from cells called glial cells, or glia, which reach out and wrap part of their fatty membranes around the extensions of nerve cells that pass electrical signals. The brain creates and renews its population of glial cells from a pool of immature cells that can develop into mature glia.
In their study, the researchers briefly deprived mice of oxygen, then gave them either 100 percent oxygen or room air, which contains about 21 percent oxygen, 78 percent nitrogen and 1 percent other gases.
After 72 hours, mice given 100 percent oxygen fared worse than those given room air. For example, they experienced a more disrupted pattern of myelination and developed a motor deficit that mimicked cerebral palsy.
The population of immature glial cells also diminished, suggesting that the animals would have trouble replacing the myelin in the long term.
"We wanted to determine whether recovery in 100 percent oxygen after this sort of brain injury would exacerbate neuronal injury and impair functional recovery, and in these animals, it did impair recovery," Dr. Kernie said. "Our research shows even brief exposure to 100 percent oxygen during resuscitation actually worsens white-matter injuries."
Dr. Kernie said adding pure oxygen to the damaged brain increases a process called oxidative stress, caused by the formation of highly reactive molecules. The researchers found, however, that administering an antioxidant, which halts the harmful oxidation process, reversed the damage in the mice given 100 percent oxygen.
"Further research is needed to determine the best possible concentration of oxygen to use for optimal recovery and to limit secondary brain injury," Dr. Kernie said. "Research is now being done to determine the best way to monitor this sort of brain damage in humans so we can understand how it correlates to the mouse models. There are many emerging noninvasive technologies that can monitor the brain."The current standard practice of giving infants and children 100 percent oxygen to... more