Glow-in-the-dark cats against AIDS, other diseases
source: http://yourlife.usatoday.com/health/healthcare/prevention/story/2011-09-12/Glow-in-the-dark-...
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ROCHESTER, Minn. -- Mayo Clinic researchers have developed a genome-based immunization strategy to fight feline AIDS and illuminate ways to combat human HIV/AIDS and other diseases. The goal is to create cats with intrinsic immunity to the feline AIDS virus. The findings – called fascinating and landmark by one reviewer — appear in the current online issue of Feline immunodeficiency virus (FIV) causes AIDS in cats as the human immunodeficiency virus (HIV) does in people: by depleting the body's infection-fighting T-cells. The feline and human versions of key proteins that potently defend mammals against virus invasion — termed restriction factors — are ineffective against FIV and HIV respectively. The Mayo team of physicians, virologists, veterinarians and gene therapy researchers, along with collaborators in Japan, sought to mimic the way evolution normally gives rise over vast time spans to protective protein versions. They devised a way to insert effective monkey versions of them into the cat genome.
The technique is called gamete-targeted lentiviral transgenesis — essentially, inserting genes into feline oocytes (eggs) before sperm fertilization. The team inserted a gene known to block cell infection by FIV, as well as a jellyfish gene for tracking purposes. The latter makes the offspring cats glow green.
http://yourlife.usatoday.com/health/healthcare/prevention/story/2011-09-12/Glow-...
The technique is called gamete-targeted lentiviral transgenesis — essentially, inserting genes into feline oocytes (eggs) before sperm fertilization. The team inserted a gene known to block cell infection by FIV, as well as a jellyfish gene for tracking purposes. The latter makes the offspring cats glow green.
http://yourlife.usatoday.com/health/healthcare/prevention/story/2011-09-12/Glow-...
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TanzaniteDiamonds
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Fascinating! Thank you for posting this.
- 9 months ago
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TanzaniteDiamonds
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bailey78
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Great skeet with feet that glow at night. Way cool. Plus it is helping to cure a sickness.
- 9 months ago
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bailey78
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BKsaysAction
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bailey78:
Wish i could splice my sister's cat with the jellyfish gene. He thinks he's sneaky now...
- 9 months ago
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BKsaysAction
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BKsaysAction
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I don't know whats bigger news. That these cats are genectically immune to aids or that they spliced jelly fish genes into the cats to make them glow in the dark.
- 9 months ago
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BKsaysAction
