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Spiders on Drugs- Just in Time for Halloween
This is amazing...this short video shows the effects of drugs on wood spiders and the unusual web formations they then create. Drugs such as THC, Cocaine and LSD are introduced to the spiders and the results are amazing... This is amazing...this short video shows the effects of drugs on wood spiders and the unusual web formations they then create. Drugs ... more
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Alzheimers..Possible change of name?
Alzheimer’s disease is a very hard disease to cope with. It not only affects the bearer of the disease, but the families as well. A person diagnosed with AD, is unwillingly entered into a death sentence of forgetfulness. The research conducted by Eric Steen, et al. investigated the characteristics of Alzheimer’s disease with any abnormal patterns related to insulin and gene expression. They hypothesized that the insulin and the insulin like growth factor expression in Alzheimer’s disease would be significantly lower than in the normal aged adult.
Eric Steen et al. received their samples from various blood banks located nationally. There samples consisted of brain tissue obtained from the brain banks. They received twenty eight Alzheimer disease brain tissue, and twenty six normal aging brain tissue. Eric Steen et. Al. determined if the brain tissues were from the “normal” aging process by reviewing the medical case studies of the “normal” aged brain tissue donors. They used various methods to measure the chemical affects of insulin and other receptors. They measured by using real time quantitative RT-PCR (reverse transcription-polymerase chain reaction). This is a great method of measuring for it can detect mRNA levels in a small sample size. They used the western blot analysis to review the amount of Akt. They used immunoprecipitation to study the “interactions between the p85 subunit of PI3 kinase and insulin receptor substrate types 1 and 2.”(E.Steen et al. pg.65).
When E.Steen et al. used the western blot analysis they found “significantly reduced mean levels of phospho-AKT “(E.Steen et al. Pg.73) this could help validate the study that is being done because AKT is involved in cell increase, programmed cell death, and diabetes. AKT was found in large numbers in the hippocampal tissue of AD Brain tissue. This research has found that insulin, and the insulin like growth factors originate from problems linked to impaired CNS growth factor production. The neurons are expressing the growth factor genes. This “raises questions and concerns about the potential benefits of peripherally administered replacement therapy.”(E.Steen et al. Pg.77) The downfall with this finding is that peripherally administered replacement therapy is the best way to administer medications without the complications of the blood brain barrier. In AD brain tissue the IGF-II expression was higher in the hippocampus area of the brain. In the control group, insulin and IGF-1 receptors were expressed at significantly greater amounts than the AD brain tissue. “In AD, insulin gene expression in the hippocampus and hypothalamus was significantly reduced relative to control (insulin gene expression was not detected in the frontal cortex.”(E.Steen et al. pg.68) This shows that AD brain tissue has a lower amount of gene expression in the areas where short term memory is stored. The human growth factor and the receptor expression were found to have significance at the .01 level when insulin was concerned. This research suggests that if AD could somehow be treated with
ligands that can increase insulin and the growth factor signaler, it can increase the life and purpose of certain neuronal cells that are at a high risk of developing AD.
My summary is from research conducted by:
“Impaired Insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer’s disease- is this type 3 diabetes?” Eric Steen, Benjamin M. Terry, Enrique J. Riviera, Jennifer L. Cannon, Thomas R. Neely, Rose Tavares, X. Julia Xu, Jack R. Wands and Suzanne M. de la Monte. Journal of Alzheimer’s Disease vol. 7 (2005). Alzheimer’s disease is a very hard disease to cope with. It not only affects the bearer of the disease, but the families as well. A ... more -
The 'Thinking Cap' that could unlock your inner genius
There is a theory that the spark of genius lurks hidden within all of us.
Now scientists are developing a 'thinking cap' that could turn that theory into practice and unlock the amazing potential of the human brain.
The device uses tiny magnetic pulses to change the way the brain works and has produced remarkable results in tests.
Wearing the hairnet-like cap for a few minutes improved artistic ability and proof-reading skills.
If the technique is perfected, the device could be marketed as a cap slipped on to boost creativity when inspiration is low.
The Australian experiments are inspired by savants, people who, like Dustin Hoffman's character in the film Rain Man, have amazing skills or talents despite a severe mental disability. There is a theory that the spark of genius lurks hidden within all of us. ... more -
LHC Breaks Down
"The Large Hadron Collider (LHC) has been halted in its tracks after developing a significant fault in one of its magnets, today. The magnetic failure follows on from problems with a faulty transformer that stopped work earlier this week.
The fault , called a 'quench', has led to the cancellation of the first trial collisions next week and could cause further delays. The transformer was replaced on Wednesday, and the beam was restored on Thursday, only for work to stop again today because of the new glitch.
However, it is much more serious as supercooled helium that chills the LHC's magnets to 1.8 centigrade above absolute zero, was released into the accelerator's 17-mile tunnel in the incident, the Times reported.
Cern refused to say how long the delay would last or what impact it would have on the experiment..." "The Large Hadron Collider (LHC) has been halted in its tracks after developing a significant fault in one of its magnets, toda... more -
United Kingdom Talk Saturday 13th September 2008
Saturday's edition of my three times a week talk show. Watch the show here on CURRENT TV on Tues, Thurs & Sats.
In today's show :
News on Joy.
Testing.
Why do we go abroad ?
Pet food advice.
Turning the machine on.
Forums.
Things discovered in inhumane ways.
My eye is observing.
Not answering the phone.
Are you of advanced years ? What did you give your pets before pet food became available ?
Mad scientists.
Broken down ? Ross will help you.
Thanks to Shaun.
A harness.
Jimmy's doing well at his new school.
We are not made to eat chemicals.
James Dean is at the top of the list if you Google matinee show.
Paying the vet.
I am a hobosexual.
No elevator for Suko.
A new gadget.
Hospital phones.
Taking on too many jobs again.
A very big experiment.
Ear wax.
Take the work while it's there.
Where's the home made marmalade gone ?
chris@unitedkingdomtalk.co.uk
WWW.UNITEDKINGDOMTALK.CO.UK Saturday's edition of my three times a week talk show. Watch the show here on CURRENT TV on Tues, Thurs & Sats. ... more -
Large Hadron Collider - LHC Interesting Facts
At worldmazingrecords.com you may find detail about Worlds Biggest Physics Experiment and interesting facts about the Large Hadron Collider at CERN.
find Amazing Interesting Facts about Large Hadron Collider - LHC
http://www.worldamazingrecords.com At worldmazingrecords.com you may find detail about Worlds Biggest Physics Experiment and interesting facts about the Large Hadron Co... more -
Experiment to unlock secrets of Big Bang could cause end of the world, say some sc...
"It has cost 4.4billion and is designed to unlock the secrets of the Big Bang.
But rather than providing vital information about the beginning of life, the world's biggest experiment could cause the end of the world, say scientists.They fear that the Large Hadron Collider - due to be switched on in a few days' time, will create a black hole that could swallow the planet.
By smashing sub-atomic particles together at close to the speed of light, the LHC aims to recreate the conditions that existed a fraction of a second after the birth of the universe or Big Bang, shedding light on the building blocks of life. But critics claim that the 'time machine', which has been built 300ft beneath the French-Swiss border near Geneva, could instead spawn a shower of mini-black holes.
The Large Hadron Collider smashes particles together at nearly the speed of light
Within four years, one of these 'celestial vacuums' could have swollen to such a size that it is capable of sucking the Earth inside-out, said Otto Rossler, one of a group of scientists mounting a last-minute court challenge to the project.
They claim the experiment violates the right to life under the European Convention of Human Rights. However, the case at the European Court of Human Rights is not expected to delay the switch on, scheduled for Wednesday September 10th.
Professor Rossler, a German chemist, said the European Organisation for Nuclear Research, or CERN, has admitted its project will create black holes but doesn't consider them to be a risk..." "It has cost 4.4billion and is designed to unlock the secrets of the Big Bang. ... more -
GMO containment?
The CBC's national news takes a look at how GM crops are being monitored in Canada.
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Self-portrait on a bicycle
Ah, this is nice: a collection of many videos all taken from exactly the same angle -- anchored to the handlebars of a bike -- collapsed and blended into one.
Spooky to watch. It sorta feels like he's riding through time itself. Ah, this is nice: a collection of many videos all taken from exactly the same angle -- anchored to the handlebars of a bike -- collaps... more -
Rodent Uses Tool in Lab Setting: Video
From the report: Degus [a rodent indigenous to the highlands of Chile] have been trained to reach through a fence, grab hold of a tiny rake and pull their favorite food, half a peeled sunflower seed, close enough to reach with their mouths. After two months of practice, researchers say, the degus can move the rake as smoothly and efficiently as croupiers in any Las Vegas casino.
The video of this little guy is so cute.. From the report: Degus [a rodent indigenous to the highlands of Chile] have been trained to reach through a fence, grab hold of a tiny... more -
The 9 largest science projects in the world!
A great list of the 9 largest science projects in the world ... either running, under construction, or on the drawing board. Who else has never heard of the Space Elevator or the "Svalbard "Doomsday" Seed Vault? A great list of the 9 largest science projects in the world ... either running, under construction, or on the drawing board. Who else ... more
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Top 10 scientists killed or injured by their experiments
Who knew science could be so risky?
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Jane Goodall Proposes Nobel Prize for Alternatives to Animal Experimentation
Goodall, whose pioneering work with chimpanzees in the wild changed the face of ethology, said that curtailing and eventually eliminating animal research is a "goal towards which all civilized nations should be moving."
"As we move into the 21st century we need a new mindset," she told attendees of a symposium organized by animal rights groups and political leaders in the European Union. "We should admit that the infliction of suffering on beings who are capable of feeling is ethically problematic and that the amazing human brain should set to work to find new ways of testing and experimenting that will not involve the use of live, sentient beings."
In the mid-90s, the Foundation rejected a suggestion from former Vice President (and recent Nobel Prize winner) Al Gore that an award be added for contributions to environmentalism. Just as Gore's recommendation would elevate the status of environmentalism in the global community, Goodall's proposal to encourage alternatives to animal experimentation would raise awareness of and appreciation for the animal protection movement and all that it stands for. Goodall, whose pioneering work with chimpanzees in the wild changed the face of ethology, said that curtailing and eventually eliminat... more -
5 psychological experiments that prove humanity is doomed
"Psychologists know you have to be careful when you go poking around the human mind because you're never sure what you'll find there. A number of psychological experiments over the years have yielded terrifying conclusions about the subjects." "Psychologists know you have to be careful when you go poking around the human mind because you're never sure what you'... more
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Do boomerangs work in space?
Takao Doi, an astronaut with the Japan Aerospace Exploration Agency, tested this three-armed paper boomerang while on the International Space Station. Takao Doi, an astronaut with the Japan Aerospace Exploration Agency, tested this three-armed paper boomerang while on the Internationa... more
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Inventor of LSD dead at 102
He became the first human guinea pig of the drug when a tiny amount of the substance seeped onto his finger during a repeat of the laboratory experiment April 16, 1943.
“I had to leave work for home because I was suddenly hit by a sudden feeling of unease and mild dizziness,” he wrote in a memo to company bosses.
“Everything I saw was distorted as in a warped mirror,” he said, describing his bicycle ride home. “I had the impression I was rooted to the spot. But my assistant told me we were actually going very fast.” He became the first human guinea pig of the drug when a tiny amount of the substance seeped onto his finger during a repeat of the lab... more -
Swiss jumps using Leonardo da Vinci-designed parachute
"A 36-year-old Swiss amateur parachutist made a successful 650-metre (2,130-foot) drop Saturday using a replica of a parachute designed more than 500 years ago by Leonardo da Vinci." "A 36-year-old Swiss amateur parachutist made a successful 650-metre (2,130-foot) drop Saturday using a replica of a parachute de... more
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Children used in Experiments
Aboriginal children in Australia were sometimes used for medical tests, it has been claimed.
Aborigine rights campaigner Kathleen Mills said she had heard of children being injected with a leprosy treatment and becoming very ill.
She said many members of the "Stolen Generations" - Aborigines taken from their homes and raised by white families - had similar experiences.
Senior politicians said they had never heard such claims before.
Ms Mills was speaking outside a Senate hearing in the northern city of Darwin, which is investigating possible compensation for the Stolen Generations. Aboriginal children in Australia were sometimes used for medical tests, it has been claimed. ... more -
Morality Experiment: Money vs. Value
MIT Behaviorists have concluded an interesting experiment. Dan Ariely, of both the MIT Media Lab and Sloan School of Management, set up situations where people could freely cheat or steal. Some results are fantastic, others understandable.
Test 1: Place a plate of six one dollar bills on a plate in common area fridges, and also place six-packs of Soda in the fridges.
Test 2: Give a test with a cash reward. Ask the subjects to score their own tests and destroy the original.
Test 3: Give a test with a cash reward. Ask half to name 10 books they have read. Ask half to name all 10 commandments.
Read on for results. MIT Behaviorists have concluded an interesting experiment. Dan Ariely, of both the MIT Media Lab and Sloan School of Management, set u... more -
Purdue students win for making hamburger assembly hella complicated
A team of Purdue University students concocted a 156-step recipe for preparing a hamburger to win Saturday's annual national Rube Goldberg Machine Contest.
This year's task was to assemble a burger consisting of no less than one precooked meat patty, two vegetables and two condiments, sandwiched between bun halves.
The victory by the 17-member Purdue Society of Professional Engineers was the team's third such win in the past four years in the contest, named for the late cartoonist known for his drawings of complicated devices performing simple tasks. Texas A&M University placed second; the University at Buffalo in New York was third.
"We put 4,000 to 5,000 man-hours into this machine since September, and all the hard work has been well worth it," said Wischer, a senior in aviation technology from Cedarburg, Wis. A team of Purdue University students concocted a 156-step recipe for preparing a hamburger to win Saturday's annual national Rube... more
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